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BA, DR, MR, DL, LS, EV, PT, IT, CS and AI performed the in silico, in vitro and in vivo studies. BA, SH-S, JL and PS analyzed knowledge and wrote the manuscript. All authors reviewed and accredited the manuscript. Retroviral particles have been generated using Plat-A cell-mediated transfection. Plat-A cells (8×105 cells/well) have been seeded 24h before transfection in 6-well plates in 2 mL/well of infection medium (Plat-A medium with out antibiotics).

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